منابع مشابه
Fat mass- and obesity-associated gene Fto affects the dietary response in mouse white adipose tissue
Common variants of human fat mass- and obesity-associated gene Fto have been linked with higher body mass index, but the biological explanation for the link has remained obscure. Recent findings suggest that these variants affect the homeobox protein IRX3. Here we report that FTO has a role in white adipose tissue which modifies its response to high-fat feeding. Wild type and Fto-deficient mice...
متن کاملAdolescent obesity adversely affects blood pressure and resting heart rate.
BACKGROUND Obesity is associated with hypertension (HT) and high resting heart rate (HR), as well as metabolic disturbances. However, little is known about how strongly these hemodynamic abnormalities are associated with the degree of obesity in adolescents. METHODS AND RESULTS Height, body weight, resting HR, and systolic and diastolic blood pressures were measured in 20,165 male and 19,683 ...
متن کاملDietary fat restriction increases fat taste sensitivity in people with obesity
OBJECTIVE Individuals with obesity may be less sensitive to the taste of fat, and it is hypothesized that this is due to excess dietary fat intake. This study assessed the effect of a 6-week low-fat (LF) or portion control (PC) diet matched for weight loss on fat taste thresholds, fat perception, and preference in people with overweight/obesity. METHODS Participants (n = 53) completed a rando...
متن کاملTrafficking of dietary fat in obesity-prone and obesity-resistant rats.
The trafficking of dietary fat was assessed in obesity-prone (OP) and obesity-resistant (OR) male and female rats. Test meals containing [1-(14)C]palmitate were delivered through gastric feeding tubes while rats consumed a high-carbohydrate diet (HCD) or after 5 days of a high-fat diet (HFD). Over the subsequent 24 h, the appearance of (14)C was followed in the GI tract, skeletal muscles (SM), ...
متن کاملSaturated fat stimulates obesity and hepatic steatosis and affects gut microbiota composition by an enhanced overflow of dietary fat to the distal intestine.
We studied the effect of dietary fat type, varying in polyunsaturated-to-saturated fatty acid ratios (P/S), on development of metabolic syndrome. C57Bl/6J mice were fed purified high-fat diets (45E% fat) containing palm oil (HF-PO; P/S 0.4), olive oil (HF-OO; P/S 1.1), or safflower oil (HF-SO; P/S 7.8) for 8 wk. A low-fat palm oil diet (LF-PO; 10E% fat) was used as a reference. Additionally, we...
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ژورنال
عنوان ژورنال: The American Journal of Clinical Nutrition
سال: 1999
ISSN: 0002-9165,1938-3207
DOI: 10.1093/ajcn/70.4.572